He got married to Ms. Surekha, daughter of Sri Allu Rama Lingaiah in 1980 when Chiranjeevi was 11 cinemas old. Allu Rama Lingaiah met Chiranjeevi first at the shooting of 'Manvoori Pandavulu'. Sri NT Rama Rao was the chief guest for the marriage.

Chiranjeevi is known for his dare devil stunts. During the shooting of Sangharshana, he was injured while doing the climax. He went to London to get operated. He was also injured when he tried fighting using Tube light in Intiguttu. In Donga cinema, he gave the producer anxious moments while fighting on a wall on 11 storied building by balancing himself. In the latest 'Bavagaru Bagunara', he did a Bungee Jumping with the carefree attitude of a teenage boy.

On October 2, 1998, he founded the Chiranjeevi Charitable Trust (CCT), which includes Chiranjeevi Blood and Eye Banks. It is the state's largest recipient of Blood and Eye Donations.The Blood Bank of the CCT helped over 80,000 people and the Eye Bank has helped about 1000 people in the state of Andhra Pradesh since its opening.So far around 3.5 lakh people have pledged their eyes to CCT so far, giving 1600 people eye sight through CCT. CCT has also won the "Best Voluntary Blood Bank Award" by the AP State Government for the past 4 years.On June 10, 2006, The President of India, Dr. Abdul Kalam, inaugurated the Chiranjeevi Charitable Foundation (CCF) at the Jubilee Hills Check post in Hyderabad.Recently Chiranjeevi charitable trust has reached one more landmark by crossing the one lakh mark in collecting the blood and more than 96,000 people were helped with blood by this blood bank.

In January 2006, Mr Chiranjeevi was honored with the Padma Bhushan., the third highest civilian award in India. In November 2006, Chiranjeevi was awarded with a honorary doctorate by Andhra University for his services to the Telugu film industry and for his social work.Chiranjeevi won the Southern Filmfare Award (Best Actor) for seven years.Chiranjeevi is one of the highest paid actors in India.Chiranjeevi's "Goli Mar (Thriller)" music video is one of the most viewed videos on Youtube.Chiranjeevi's old hit movies are given to the distributors and exhibitors for free when ever they lose money on his new movie. And his old movies are still successful at the box office.